Found: 9
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021
Imaeva A.K., Gallyamova L.F., Nurgaliyeva A.Kh., Mustafin T.I., Khusnutdinova E.K.
Introduction. Molecular genetic research methods suggest the development of certain forms of pancreatitis and its complications. Aim of the study. Identification of risk factors for the development of acute forms of pancreatitis based on molecular genetic stud…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020
Savkova A.V., Gerasimov A.V., Vasiliev G.V., Krasilnikov S.E., Gulyaeva L.F., Voitsitsky V.E.
Introduction. Multiple primary malignant neoplasms (MPMN) most often develop in individuals with a hereditary predisposition to oncological diseases. There are inherited allelic variants of oncogenes, tumor suppressor genes and their combinations which disrupt…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019
Solov’eva N.V., Makarova E.V., Vil’yanov V.B., Kremenitskaya S.A., Chausova S.V., Kichuk I.V., Shibalev D.V., Vasilyev V.A.
Introduction. The androgen receptor (AR) gene MIGHR is known to be associated with transsexualism. Bone tissue is one of the target organs for androgens. Trochanteric index (TI) (ratio of height to the leg length) may indicate the organism androgenization leve…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018
Ponomarenko I.V., Prashchayeu K.I., Shaginyan G.G., Churnosov M.I., Ilnitski A.N., Khrokhmaliova E.V.
Introduction. Endometrial hyperplasia represents a chronic progressive disease characterized by high prevalence among women in older age groups. The aim of the study. To study the involvement of combinations of candidate genes in the formation of hyperplastic …
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017
Bovt P.A., Vishnevskaya T.V., Nurmukhametova E.A., Blokhina N.P., Deryabin P.G., Samokhvalov E.I., Kolobukhina L.V., Khlopova I.N., Kelly E.I., Malyshev N.A., AlkhovskyS.V.
Introduction. Hepatitis C virus (HCV) is a major risk factor for chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. Molecular mechanisms of fibrogenesis are associated with the activation or inhibition of signaling pathways, which are controlling…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016
Altukhova O.B., Ponomarenko I.V., Demakova N.A., Prashchayeu K.I., Churnosov M.I., Shaginyan G.G.
Introduction. Uterine fibroids – a benign tumor, growing from immature muscle cells of the vascular wall of the uterus. It ranked first among the benign tumors of the genital organs, with one in ten suffers from gynecological patients with uterine myoma. The a…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016
Sin’kov V.V., Ogarkov O.B., Mokrousov I.V., Zhdanova S.N.
Introduction. Russian population of Mycobacterium tuberculosis includes both highly virulent and less virulent strains; the Ural genotype makes an example of the latters. The aim of study was investigation of the most significant synonymous and non-synonymous …
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015
Ludannyy R.I., Alvarez Figueroa M.V., Prokopenko A.V., Valdokhina A.V., Shipulin G.A.
Introduction. The phenomenon of drug resistance of Mycobacterium tuberculosis complex is extremely complicated. The determination of the genetic changes is not always able to explain reasons of this effect clearly. The aim of the study. Molecular genetic analy…
Research article2014
Vorsanova S.G., Iourov I.Yu., Voinova V.Yu., Kurinnaya O.S., Zelenova M.A., Demidova I.A., Yurov Yu.B.
Introduction. Rett syndrome (RTT) is the most common genetic syndrome underlying mental retardation and autism in girls. Etiology of this disorder is related to mutation in the MECP2 gene. However, there are many cases of this disease without the MECP2 mutatio…