Search

SOMATIC AND GERMLINE MUTATIONS IN GASTRIC CANCER

Nemtsova M.V., Tanas A.S., Alekseeva E.A., Bykov I.I., Zaletayev D.V., Khorobrykh T.V., Strelnikov V.V.

Introduction. Most cases of gastric cancer (GC) occur sporadically. Until recently, diffuse hereditary gastric cancer associated with the CDH1 gene mutations was considered the only hereditary form (about 1–3% of all tumors of the stomach). However, a signific…