ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015
Nemtsova M.V., Tanas A.S., Alekseeva E.A., Bykov I.I., Zaletayev D.V., Khorobrykh T.V., Strelnikov V.V.
Introduction. Most cases of gastric cancer (GC) occur sporadically. Until recently, diffuse hereditary gastric cancer associated with the CDH1 gene mutations was considered the only hereditary form (about 1–3% of all tumors of the stomach). However, a signific…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015
Tsukanov A.S., Pospekhova N.I., Shubin V.P., Sachkov I.Yu., Achkasov S.I., Rybakov E.G., Frolov S.A., Kashnikov V.N., Shelygin Yu.A.
Aim. Lynch Syndrome, which is caused by a defect in one of the mismatch repair (MMR) genes, is the most common among all hereditary colorectal cancer syndromes. Patients with Lynch syndrome in different populations are inherent in both genetic and clinical fea…