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Molecular Medicine Peer-reviewed scientific journal

Found: 5

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 79–88

Glutathione: a key molecule of redox homeostasis and its potential for nutritional and metabolic regulation. a review of the literature

Introduction. Glutathione (GSH) is a key intracellular antioxidant involved in maintaining redox homeostasis, detoxifying xenobiotics, regulating immune and neurotransmitter systems, and supporting protein folding and degradation. Depletion of GSH is associate…

10.29296/24999490-2025-05-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

A MODEL OF SURFACE PLASMON RESONANCE IMMUNOSENSOR FOR DETERMINING AUTOANTIBODIES TO GLUTATHIONE-S-TRANSFERASE IN SERUM SAMPLES

Introduction. The quantitative determination and isotyping of autoantibodies to a clinically significant protein – glutathione-S-transferase (GST) in blood serum samples is relevant for monitoring and predicting the dynamics of autoimmune processes. The aim of…

10.29296/24999490-2020-06-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

ALTERATION OF HYDROPEROXIDE NON-STEADY STATE GRADIENTS IN THE REOXYGENATION NIDUS EXPOSED TO GLYCINE UNDER EXCITOTOXICITY

Introduction. Glycine is well-known to have a positive effect in the treatment of patients suffered from an ischemic stroke. Vasodilatation is one of the main parts of the action of this amino acid at the molecular level. Simultaneously, the increase of oxygen…

10.29296/24999490-2018-03-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

OXIDATIVE AND NITROSATIVE STRESSES ON THE TRANSLATIONAL MODEL OF DIABETES; NORMALIZING EFFECT OF PRO-GLY-CONTAINING DIPEPTIDE, NOOPEPT

Introduction. Oxidative and nitrosative stresses are reported to be an important pathogenic factors of diabetes. Taking into account our previous findings that Noopept (N-phenyl-acetyl-L-prolyl-glycine ethyl ester) attenuates the hyperglycemia, decrease of inc…

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