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Molecular Medicine Peer-reviewed scientific journal

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 24–33

Transcription factors bioinformatic analysis of differential gene expression in b16 melanoma cells under antitumor alkylating agent application

Introduction. Cancer drug resistance is driven among others, by non-genetic mechanisms. These processes may involve transcription factors dysregulation, modifications in gene expression, as well as epigenetic mechanisms such as DNA methylation, histone modific…

10.29296/24999490-2026-03-04Details ↗
Research article2013

EPIGENETIC EFFECTS OF MINOR GROOVE BINDING LIGANDS

The influence of the DNA minor groove binding ligands on epigenetic silencing in eukaryotic human cells has been demonstrated for the first time. Using HeLa cell population that harbors silent GFP-reporter gene under control of the CMV promoter we demonstrated…

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