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A COMPARATIVE IMMUNOCYTOCHEMICAL ANALYSIS OF DNA METHYLATION PATTERNS IN HUMAN METAPHASE CHROMOSOMES OF ADULTS AND FETUSES

Efimova O.A., Pendina A.A., Tikhonov A.V., Chiryaeva O.G., Petrova L.I., Dudkina V.S., Sadik N.A., Kuznetzova T.V., Baranov V.S.

Introduction. DNA methylation is a key epigenetic modification providing the regulation of human genome activity in ontogenesis. DNA methylation patterns were described in the chromosomes from adult lymphocytes. DNA methylation patterns of the chromosomes from…