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POSSIBLE APPLICATIONS OF UMBILICAL CORD BLOOD HEMATOPOIETIC STEM CELLS WITH CCR5-DELTA 32/DELTA 32 GENOTYPE FOR THE TREATMENT OF HIV INFECTION

Smolyaninov A.B., Chechetkin A.V., Pirozhkov I.A., Ivolgin D.A.

Introduction. Binding of the human immunodeficiency virus (HIV) envelope gp120 glycoprotein to CD4 and CCR5 receptors on the cell membrane initiates the viral entry process. Simultaneous expression of these two receptors has been observed on T-lymphocytes, mon…