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Spatial analysis of tissue microenvironment functional morphology: multidimensional visualization techniques and artificial intelligence

Atiakshin D.A., Poddubsky A.A., Demyashkin G.A., Rezaian N., Saridis M.R., Prikhodko A.T., Alekhnovich A.V., Kostin A.A., Paltseva Е.М

Objective. To systematically categorize contemporary approaches and technologies for visualizing structural components of the tissue microenvironment (TME), with a focus on the advantages, limitations, and data analysis strategies of multiplex immunohistochemi…