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Molecular Medicine
Found: 2
Introduction. Sirtuins (SIRTs) are NAD+-dependent histone deacetylases involved in the intracellular regulation of multiple biological processes including DNA repair, autophagy, inflammation, oxidative stress defence and metabolism associated with age-associat…
Introduction. Proinflammatory cytokines produced in elevated concentrations in the elderly significantly impair neurogenesis in the dentate gyrus of the hippocampus, long-term potentiality, alter neuronal morphology and function, and increase apoptosis. This l…