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ANALYSIS OF HERMINAL MUTATIONS IN ONCOGENES AND TUMOR SUPPRESSOR GENES IN WOMEN WITH MULTIPLE PRIMARY MALIGNANT NEOPLASMS

Savkova A.V., Gerasimov A.V., Vasiliev G.V., Krasilnikov S.E., Gulyaeva L.F., Voitsitsky V.E.

Introduction. Multiple primary malignant neoplasms (MPMN) most often develop in individuals with a hereditary predisposition to oncological diseases. There are inherited allelic variants of oncogenes, tumor suppressor genes and their combinations which disrupt…