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COMPLEX F8 GENE REARRANGEMENTS

Beskorovainaya T.S., Milovidova T.B., Shchagina O.A., Matushchenko E.G., Petuhova M.S., Togochakova O.K., Salomashkina V.V., Pshenichnikova O.S., Surin V.L., Polyakov A.V., Ginter E.K.

Introduction. Hemophilia A is a frequent X-linked recessive disorder associated with the absence or functional defect of blood clotting factor VIII. Вoth point mutations and large structural rearrangements – deletions, duplications, and inversions were describ…