ОБЗОР2025 · pp. 66–75
Trofimova S.V., Kuznetsova T.G., Trofimov A.V.
Introduction. Short peptides are considered a promising class of geroprotective agents capable of modifying key molecular mechanisms of aging, from epigenetic regulation of gene expression to maintenance of neuroendocrine and antioxidant homeostasis. Laborator…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 20–26
Panchenko Al.V., Panchenko An.V., Pavlova L.E., Timina M.F., Cherkashina E.V., Kolik L.G., Seredenin S.B.
Introduction. The developed domestic dipeptide retro-analog of cholecystokinin (CCK) tetrapeptide (N-(6-phenylhexanoyl)-glycyltryptophan amide, compound GB-115) with antagonistic properties towards CCK1 receptors has anxiolytic activity, previously shown in pr…