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Molecular Medicine Peer-reviewed scientific journal

Found: 12

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 31–39

The effect of a high-fat diet and phytocomposition based on B. vulgaris, C. bergamia, D. villosa and L. meyenii on the expression of genes for carbohydrate and lipid metabolism enzymes in the liver of rats

Introduction. The liver serves as a buffer for the accumulation and utilization of excess intake of nutritional fats, the intake of plant compounds can improve metabolic processes in the liver, but the molecular mechanisms of this phenomenon have been little s…

10.29296/24999490-2025-05-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 108–115

The Impact of Low Doses of Ethanol on the Taxonomic Composition and Biodiversity of the Microbiota in the Small and Large Intestines of C57Bl6 mice

Alcohol consumption has a detrimental effect on human health and is associated with various pathological changes in the body. In addition to the toxic effect on various tissues and organs, ethanol and its metabolites contribute to persistent changes in the com…

10.29296/24999490-2025-03-14Details ↗
ОБЗОР2023 · pp. 3–10

PROTEINS TIMP-2, IRISIN AND SITUATION WITH HEMOSTASIS, LIPID METABOLISM AND SEX HORMONES IN FEMALE CARDIOVASCULAR PATIENTS

Introduction. The study of the level of the so-called «youth proteins» TIMP-2 and irisin in diseases of the cardiovascular system is not only of theoretical interest, but also of practical importance, as it outlines new ways to treat these diseases. Purpose of…

10.29296/24999490-2023-04-01Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 53–59

THE GENDER FACTOR EFFECT FOR THE EDOCRYNE FUNCTION OF MESENCHYMAL TISSUES IN CHILDREN AND ADOLESCENT

Introduction. There is take place increasing in the incidence of obesity among children and adolescents in the world. However, until now there are not exist clear views about mechanisms of that phenomenon. The aim of study. The purpose of that work is comparat…

10.29296/24999490-2023-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 42–52

ASSOCIATION OF POLYMORPHIC VARIANTS OF NON-ALLELIC GENES ADIPOQ, MTHFR, PON1, KCNJ11, TCF7L2, ITLN1 AND PPARG WITH CLINICAL AND LABORATORY PARAMETERS AMONG OBESE PATIENTS FROM KYRGYZ REPUBLIC

Introduction. In Kyrgyzstan about 60% of the adult population suffers from lipid metabolism disorders of varying degrees. Early identification of persons at increased risk of developing obesity is of great importance, which can be achieved through the study of…

10.29296/24999490-2022-05-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

QUANTITATIVE DISTRIBUTION OF APOLIPOPROTEIN-E AMONG BLOOD PLASMA LIPOPROTEINS IN HEALTHY MEN

Introduction. Apolipoprotein-E (apoE), being one of the metabolically active apoproteins plays the important role in lipid metabolism. The aim of the study was to investigate the quantitative distribution of apoE between different lipoprotein classes in health…

10.29296/24999490-2018-05-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

PROTEOMIC AND METABOLOMIC MANIFESTATIONS OF DIFFERENT VARIANTS OF APOLIPOPROTEIN E GENES POLYMORPHISM IN OBESE PATIENTS

Introduction. Currently questions on the role of genes polymorphism that regulate metabolism and implicated in metabolic disorders are disputed. Objective. The study of proteomic and metabolomic manifestations of different variants of apolipoprotein E genes po…

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ОБЗОР2017

EFFECT OF HUMAN MICROBIOTA ON THE CARDIOVASCULAR SYSTEM

In the presented review a new potential risk factor for atherosclerosis and cardiovascular disease such as microflora of the human gastrointestinal tract is considered. The modern concept of lipid metabolism and its effects on human health outlining the basic …

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

EVOLUTIONARY SIGNIFICANCE OF NON-SYNONYMOUS SUBSTITUTIONS FOR MYCOBACTERIUM TUBERCULOSIS OF URAL GENOTYPE

Introduction. Russian population of Mycobacterium tuberculosis includes both highly virulent and less virulent strains; the Ural genotype makes an example of the latters. The aim of study was investigation of the most significant synonymous and non-synonymous …

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

GENERAL AND SPECIFIC IN THE GENOME OF PATIENTS WITH TYPE 1 AND TYPE 2 DIABETES

Introduction. Diabetes mellitus type 1 and type 2 are having a number similar etiological factors and certain resemblance in the mechanisms of the disease. Therefore it is important to try to estimate the role of common genetic component in the genesis and for…

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