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Molecular Medicine
Found: 3
Introduction. The elevated expression of components of DNA repair system ERCC1 (excision repair cross-complementing group 1) and XPD (Xeroderma pigmentosum group D) is associated with the lack of efficacy of DNA–damaging cytotoxic platinum-based preparations. …
The prognosis of one of the most commonly occurring malignancies worldwide – colorectal cancer (CRC) – depends on the development of disease recurrence and distant metastases, most frequently detected in the liver. The aim of our research was to study the asso…
The modern strategies of chemotherapy of metastatic colorectal cancer (CRC) based on the combination of cytotoxic and targeted angents resulted in significant increase of patient’s life duration. To study the action of anti-EGFR agents (panitumumab), which blo…