ОБЗОР2025 · pp. 41–49
Olgin O.E., Zheravin A.A., Aliev M.D., Choynzonov E.L., Chernyshova A.L., Tamkovich S.N.
Relevance. Primary malignant neoplasms of bones and articular cartilage account for about 0.2% of all cancer cases and are characterized by an aggressive course, high tendency to metastasize, and resistance to therapy, which leads to unsatisfactory survival ra…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 25–32
Gershtein E.S., Kuzmin Yu.B., Alferov A.A., Korotkova E.A., Tsarapaev P.V., Sokolov N.Yu., Kuznetsov I.N., Vashketova O.I., Kozlova E.M., Yanushevich O.O., Boulytcheva I.V., Stilidi I.S., Kushlinskii N.E.
Background. Low sensitivity of bone tumors to various schemes of standard chemotherapy stimulated the search of new targets for their medicamentous treatment. Among such targets are the so-called “immune checkpoints” promoting the escape of the tumor from the …