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Molecular Medicine Peer-reviewed scientific journal

Found: 7

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2026 · pp. 31–38

Proteomic reprogramming of senescent mesenchymal stromal cells of adipose tissue: a role in the modulation of macrophage phenotype and the formation of inflammageing in obesity

The study is devoted to the identification of changes in the proteomic profile of senescent mesenchymal stromal cells of adipose tissue, which determine the modulation of the macrophage phenotype and are involved in the pathogenetic cascade of the formation of…

10.29296/24999490-2026-02-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 44–49

POSSIBILITIES OF APPLICATION OF ALLOGENIC TISSUE ENGINEERING PRODUCTS IN THE EXPERIMENTAL URINARY BLADDER RECONSTRUCTION

The article describes the results of an experimental study of tissue-engineering constructions based on lactic acid – poly-L,L-lactide, containing allogeneic cells of various tissue origin. Aim: to show experimentally the possibility of using an allogeneic tis…

10.29296/24999490-2022-06-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

THE SOME PECULIARITIES OF CAPSULAR FORMATION AFTER IMPLANTATION OF SILICONE WITH ADSORBED MULTIPOTENT MESENCHYMAL STROMAL CELLS

Introduction. The widespread cellular technologies will sooner or later lead inevitably to the introduction of multipotent mesenchymal stromal cells (MMSC) or their exosomes to patients who have implanted artificial materials in their organism. The engraftment…

10.29296/24999490-2019-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

MACROPHAGAL ADSORPTION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS AND THEIR DEBRIS FROM VASCULAR BED PROVES THE MIGRATION OF THESE CELLULAR ELEMENTS THROUGH THE VESSELS AFTER TISSUE INJECTION

Introduction. The use of cell technologies has particular effectiveness in the treatment of many diseases. However, the literature contains data concerning macrophages ability of a phagocytosis and lysisofautologic multipotent mesenchymal stromal cells of a bo…

10.29296/24999490-2018-04-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE POSSIBILITY OF THE ANGIOGENESIS IN TISSUES REMOTE FROM THE PLACE OF THE MULTIPOTENT MESENCHYMAL STROMAL CELL INJECTION

Introduction. The use of cell technologies has particular effectiveness in the correction of the experimental venous thrombosis and acute local obstruction to the blood outflow. Autologic multipotent mesenchymal stromal cells of a bone marrow origin (AMMSCBMO)…

10.29296/24999490-2018-03-04Details ↗
ОБЗОР2016

MESENCHYMAL STEM CELLSAND PEPTIDES: ROLE AND IMPORTANCE INMOLECULARMECHANISMS OFTARGETED THERAPY

Review is devoted to systems for drug delivery of biologically active substances in the tissues and organs of the target cells, which is relevant to medicine. There are described properties of mesenchymal stromal cells (MSCs), which many authors propose to use…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

THE SPONTANEOUS DELIVERY AFTER CORRECTION OF HYDROMETRA BY ADMINISTRATION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS IN EXPERIMENT

Introduction. The angiogenesis in a uterus scar after application of multipotent mesenchymal stromal cells of a bone marrow origin (MMSCBM) was shown. However, possibility of approach of pregnancy and spontaneous deliveries in rats after MMSCBM introduction in…

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