Search

METHYLATION INVOLVEMENT IN REGULATION OF EXPRESSION OF FUNCTIONALLY SIGNIFICANT GENES ON CHROMOSOME 3: RHOA, GPX1, USP4, DAG1, NKIRAS1 IN BREAST CANCER

Loginov V.I., Pronina I.V., Burdennyy A.M., Khodyrev D.S., Kazubskaya T.P., Braga E.A., Kubatiev A.A., Kushlinskii N.E.

Introduction. Epigenetic changes caused by methylation in promoter CpG-islands are a fine and dynamic mechanism of gene expression regulation in tumors. Increased and decreased expression and alterations in the methylation status of the gene are considered to …