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Activation of the MAPK signal cascade components phosphorylation involved in the formation of the G0-positive tumor phenotype

Esimbekova A.R., Lapkina E.Z., Ruksha T.G.

Introduction. Among the heterogeneous population of tumor cells, there are so-called dormant and senescent cells located in the G0 phase of the cell cycle. The transition to the G0 phase is a stress response mediated, for example, by treatment with chemotherap…