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INTERLEUKIN-6 RECEPTOR GENE POLYMORPHISM IS ASSOCIATED WITH BOTH INCREASED INTERLEUKIN-6 BLOOD LEVEL AND BIOPROSTHETIC MITRAL VALVE CALCIFICATION

Ponasenko A.V., Khutornaya M.V., Kutikhin A.G., Khryachkova O.N., Kondyukova N.V., Yuzhalin A.E., Rutkovskaya N.V., Barbarash O.L., Barbarash L.S.

Introduction. Valvular calcification precedes the development of valvular stenosis. Currently, there being no way to effectively prevent the valvular heart disease progression, and valve replacement remains to be the only treatment option. Aim. To investigate …