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Molecular Medicine
Found: 15
Introduction. The study of mechanisms of multicellular system regulation and of cellular proliferation balanced status in the organism tissues is one of the actual task of modern biology and medicine. Purpose of study. Effect of encoded amino acids combination…
Among a very significant number of possible variants of posttranslational modifications (PTM) affecting the contractile function of the myocardium, the most significant effect is exerted by posttranslational phosphorylation of protein components of the contrac…
Introduction. Mitochondria are one of the most important cellular organelles that provide cells with energy, take part in cellular renewal and the implementation of endogenous mechanisms of cellular immunity. The study of the structural and functional organiza…
Introduction. The investigations of the magnetic-biological effects are actual because of the permanent impact of changing Earth geomagnetic field on the live organisms. Purpose of the study was to investigate the impact of the weakened geomagnetic field (WGF)…
Introduction. Developing of chronic emotional stress reduces adaptive capabilities of people ill with diabetes mellitus causing the condition of decompensation with significant elevation of counterinsular hormones production and further progressive metabolic d…
Introduction. The investigations of the magnetic-biological effects are actual because the modern technical works are related to the constant magnetic field (CGF) Purpose of the study was the investigation of impact of (CMF) on the tissues of various genesis –…
Cardiomyopathies are diseases that affect the heart muscle. They are characterized by myocardial dysfunction in the absence or low severity of common cardiovascular diseases, such as coronary atherosclerosis, hypertension, valvular heart diseases. Cardiomyopat…
This article provides a modern analysis of the literature on the mechanisms of activation of mast cells (MC) because they are regulatory cells that make up an important part of the immune system and are part of the first line of defense against various patholo…
Introduction. Alcoholic cardiomyopathy is the leading cause of death in persons withchronic alcoholism. This disease is caused by ethanolinduced toxic damage to the heart muscle, which leads to dilated heart failure and the development of the electric myocardi…
In the presented review a new potential risk factor for atherosclerosis and cardiovascular disease such as microflora of the human gastrointestinal tract is considered. The modern concept of lipid metabolism and its effects on human health outlining the basic …
The purpose of this study. Evaluation the effect of Afobazol on the level of myocardial inducible NO-synthase (iNOS) in the ischemic myocardium in rats. Methods. Myocardial ischemia was produced by the Selye’s method. The of inducible NO-synthase level on the …
The aim of the study. The proof of afobazole efficacy for treatment and prevention of alcoholic cardiomyopathy and attendant complications using the previously developed translational model. Materials and methods. Alcoholic cardiomyopathy was produced by conti…
The aim of the study – the development of translational models of the alcoholic cardiomyopathy in rats to search and study the action mechanism of new original drugs for the treatment of this pathology. Methods. The complex of echocardiographic, electrophysiol…
Morphometric studies of the median transverse sections of rat hearts, performed on 28th day after coronary artery ligation, showed that as a result of myocardial infarction the pronounced postinfarction remodelling of the left ventricle of the heart was observ…
Among a very significant number of possible variants of posttranslational modifications (PTM) affecting the contractile function of the myocardium, the most significant effect is exerted by posttranslational phosphorylation of protein components of the contrac…