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Molecular Medicine Peer-reviewed scientific journal

Found: 3

ОБЗОР2024 · pp. 16–22

Biomarkers of oxidative stress and proteopathies in the diagnosis of neurodegenerative diseases

Introduction. Despite numerous studies in the field of neurodegenerative diseases, the exact mechanisms of these processes have not yet been identified. The purpose of this review is to analyze the methodological approaches necessary to revise the traditional …

10.29296/24999490-2024-02-03Details ↗
ОБЗОР2023 · pp. 12–21

MOLECULAR MECHANISMS OF NEUROINFLAMMATION AND SLEEP DEPRIVATION IN THE DEVELOPMENT OF AGE-ASSOCIATED COGNITIVE DYSFUNCTION

Introduction. Proinflammatory cytokines produced in elevated concentrations in the elderly significantly impair neurogenesis in the dentate gyrus of the hippocampus, long-term potentiality, alter neuronal morphology and function, and increase apoptosis. This l…

10.29296/24999490-2023-03-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

RELATIONSHIP BETWEEN OXIDATIVE PROTEIN MODIFICATION AND THE ACTIVITY OF LYSOSOMAL CYSTEINE PROTEINASES IN BLOOD PLASMA AND LEUKOCYTES IN ALZHEIMER’S DISEASE

Introduction. Revealing the relationship between the severity of oxidative stress and the activity of cathepsins in tissues (plasma and blood cells) readily available for the diagnosis of Alzheimer’s disease can be useful for understanding the pathogenesis of …

10.29296/24999490-2020-06-07Details ↗

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