ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020
Engalycheva M.G., Fomina M.A., Petrov D.S., Tazina T.V.
Introduction. The development of neurodegeneration in Alzheimer’s disease is inextricably linked with oxidative stress, a marker of which is oxidative protein modification. In the tissues of the brain, cerebrospinal fluid and plasma in Alzheimer’s disease, an …
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020
Engalycheva M.G., Korotkova N.V., Petrov D.S., Sokolov V.A., Ryabkov A.N.
Introduction. Revealing the relationship between the severity of oxidative stress and the activity of cathepsins in tissues (plasma and blood cells) readily available for the diagnosis of Alzheimer’s disease can be useful for understanding the pathogenesis of …
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015
Stepovaya E.A., Ryazantseva N.V., Nosareva O.L., Zakirova E.V., Naumova A.I., Vesnina O.N., Orlov D.S., Shakhristova E.V., Ivanov V.V., Novitsky V.V.
Introduction. According to modern understanding, oxidative stress along with apoptosis dysregulation plays an important role in the pathogenetic mechanisms of tumor growth; formation of oxidative stress is accompanied by oxidative modification of cell protein …