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Molecular Medicine
Found: 7
Introduction. Innate immunity represents the first line of defense against pathogens, based on recognition of conserved molecular patterns (PAMPs) through specialized pattern recognition receptors (PRRs). RNA-containing viral patterns are of particular importa…
Introduction. An increasing number of reports of long-term negative consequences of COVID-19, characterized by chronic inflammation, tissue hypoxia, oxidative stress, metabolic changes at the level of all body systems, determines the search for criteria for as…
Introduction. Among the heterogeneous population of tumor cells, there are so-called dormant and senescent cells located in the G0 phase of the cell cycle. The transition to the G0 phase is a stress response mediated, for example, by treatment with chemotherap…
Among a very significant number of possible variants of posttranslational modifications (PTM) affecting the contractile function of the myocardium, the most significant effect is exerted by posttranslational phosphorylation of protein components of the contrac…
Energy supply of cells can be provided through both an oxygen-dependent pathway of mitochondrial oxidative phosphorylation and oxygenindependent glycolysis. Oxidative phosphorylation in the synthesis of ATP is more efficient than in glycolysis, and respectivel…
Introduction. Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of GI tract, are characterized by KIT and PDGFRA activating mutations that are predictive factors. KIT and PDGFRA mutations are present in 85% of GISTs and are associated…
Among a very significant number of possible variants of posttranslational modifications (PTM) affecting the contractile function of the myocardium, the most significant effect is exerted by posttranslational phosphorylation of protein components of the contrac…