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Transformation of spiral arteries during pregnancy: pathogenic parallels between preeclampsia and placenta accrete spectrum

Nizyaeva N.V., Milyutina E.R., Makhmutova M.R., Plakhotina E.N., Fokina T.V., Gabitova N.A., Adamov Y.I., Belousova T.N.

Introduction. Spiral artery transformation is a key physiological process of pregnancy that establishes low-resistance uteroplacental blood flow. It involves trophoblast invasion of the vascular wall, replacement of the endothelium, and disruption of the smoot…