ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018
THE PREVALENCE OF CYP2C19*2, *3 POLYMORPHISMS AMONG RUSSIANS AND YAKUTS WITH PEPTIC ULCER DISEASE, LIVING IN SAKHA REPUBLIC (YAKUTIA)
Introduction. Proton pump inhibitors (PPI) are widely spread as antisecretory drugs for a treatment of acid diseases, such as the gastric ulcer. Most of the proton pump inhibitors are inactivated in the liver by cytochromes P450 2C19 (CYP2C19) to the form of i…