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Molecular heterogeneity of obesity: psychobiological mechanisms, limitations of the diagnostic model, and prospects for the development of personalized diagnosis and treatment

Grinevich V.B., Zakrevsky V.V., Kravchuk Yu.A., Salikova S.P., Seliverstov P.V., Dikinova K.A., Khupsergenova I.N., Gorbunova D.I., Khabibulina M.M.

Introduction. Obesity can no longer be adequately described by body mass index alone. Similar BMI values may coexist with different fat distribution, inflammatory burden, neuroendocrine dysregulation, psychobehavioral traits, and risks of organ dysfunction. Ob…