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Molecular Medicine Peer-reviewed scientific journal

Found: 9

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 10–20

Biochemical markers of inflammation in drug-resistant tuberculous meningitis (experimental study)

Introduction. The determination of inflammatory markers used to monitor the course of the disease and monitor the effectiveness of treatment. Goal. To evaluate biochemical markers of inflammation in cerebrospinal fluid (CSF) and blood serum in experimental men…

10.29296/24999490-2025-05-02Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 92–100

Morphological features of atherosclerotic plaque: modeling of atherosclerosis after stenting as a model of premature aging

Atherosclerosis and the installation of stents can be considered as a model of premature aging of the body. These processes are associated with chronic inflammation, oxidative stress, loss of cellular function, and impaired regeneration, which makes them a con…

10.29296/24999490-2025-03-12Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 68–76

Features of local synthesis of neurotrophic factors under the influence of fractal stimulation phototherapy in a model of retinal pigment epithelium atrophy on rabbit

Introduction. It is assumed that in degenerative diseases of the retina, photostimulation with fractal dynamics signals activates neuroplasticity, increasing the effectiveness of visual rehabilitation. Previously, we demonstrated the positive effect of fractal…

10.29296/24999490-2025-03-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 52–58

LOCAL PRODUCTION OF NEUROTROPHIC FACTORS UNDER THE INFLUENCE OF FRACTAL STIMULATION PHOTOTHERAPY ON THE RETINA OF RABBITS

Introduction. Recently, a new approach to visual response has been discussed, based on the use of optical signals of a heavy structure, manifested by fractal dynamics. However, the molecular mechanisms of action of fractal phototherapy (FF) have not been studi…

10.29296/24999490-2023-05-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 27–35

USE OF MESENCHYMAL STEM CELLS IN COMPLEX TREATMENT OF DRUG-RESISTANT RENAL TUBERCULOSIS (EXPERIMENTAL STUDY WITH MORPHOLOGICAL CONTROL)

Introduction. The use of mesenchymal stem cells (MSCs) is recognized as a promising direction for the treatment of diseases with a predominance of inflammation and sclerosis in the pathogenesis, which includes nephrotuberculosis (NT). Target. Studying the effe…

10.29296/24999490-2023-05-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 29–38

CHANGES IN RETINAL VASCULAR STRUCTURE AND BLOOD BIOCHEMICAL MARKERS OF MODELED WHITE RATS IN SHORT-TERM ARTERIAL HYPERTENSION

Introduction: Great progress has been made in the treatment of arterial hypertension (AH). However, despite the fact that new technologies have paved the way for practical medicine, the number of deaths and disabilities from diseases of the cardiovascular syst…

10.29296/24999490-2023-03-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 44–49

POSSIBILITIES OF APPLICATION OF ALLOGENIC TISSUE ENGINEERING PRODUCTS IN THE EXPERIMENTAL URINARY BLADDER RECONSTRUCTION

The article describes the results of an experimental study of tissue-engineering constructions based on lactic acid – poly-L,L-lactide, containing allogeneic cells of various tissue origin. Aim: to show experimentally the possibility of using an allogeneic tis…

10.29296/24999490-2022-06-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

Features of local expression of mRNA, IL-1β, IL-18, CCL2/MCP-1 in modeling pigment epithelium atrophy and retinal degeneration in the experiment on rabbits

Introduction. Degenerative retinal diseases are considered as the leading cause of blindness and low vision worldwide. The last studies have provided convincing evidence of the involvement of immunological factors in the development and progression of the dise…

10.29296/24999490-2021-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

DELIVERY OF MITOMYCIN C AND PROLONGATION OF ITS ACTION OWING TO THE USУ OF NEW HYDROGELS OF HYALURONIC ACID AND CHITOSAN SUCCINATE FOR GLAUCOMA SURGERY

Purpose an experimental evaluation of the effectiveness of new hydrogels based on hyaluronic acid and chitosan succinate as an agent of mitomycin C (MMC) for glaucoma surgery. Material and methods. Synthesis of hydrogel drainage (HD): The required amount of MM…

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