Found: 4
ОБЗОР2025 · pp. 66–75
Trofimova S.V., Kuznetsova T.G., Trofimov A.V.
Introduction. Short peptides are considered a promising class of geroprotective agents capable of modifying key molecular mechanisms of aging, from epigenetic regulation of gene expression to maintenance of neuroendocrine and antioxidant homeostasis. Laborator…
ОБЗОР2021
Kucher A.N.
Sarcopenia is a progressive and generalized pathology of skeletal muscles of multi-factor nature. The present review focuses on the analysis of molecular genetic markers that may contribute both to sarcopenia risk formation and the variability of diagnosticall…
ОБЗОР2017
Kit O.I., Vodolazhsky D.I., Timoshkina N.N.
The frequency of reported cases of melanoma and related mortality rates continue to increase worldwide. The study of the basic mechanisms of both the initiation and development of this highly aggressive tumour proves to be important for the identification of t…
Research article2014
Loginov V.I., Pronina I.V., Burdennyy A.M., Khodyrev D.S., Kazubskaya T.P., Braga E.A., Kubatiev A.A., Kushlinskii N.E.
Introduction. Epigenetic changes caused by methylation in promoter CpG-islands are a fine and dynamic mechanism of gene expression regulation in tumors. Increased and decreased expression and alterations in the methylation status of the gene are considered to …