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Molecular Medicine
Found: 15
Cardiovascular diseases remain one of the main causes of hospitalization, disability, and mortality. The usual monitoring model and rare face-to-face visits often do not keep up with the actual clinical dynamics. This partly explains the growing interest in we…
The pathogenetic process of sarcopenic obesity (SO) development is multifactorial, the key of them is considered – non-specific systemic inflammation. Objective. to assess the influence of the intensity of the course of chronic inflammation in patients with ty…
Introduction. To date, digital twins are the most promising area for the development of modern healthcare. With their help, it is possible to radically change approaches to the diagnosis, treatment and prevention of diseases. In medicine, the concept of digita…
Introduction. The significant increase in obesity among children and adolescents necessitates the search for ways to prevent and treat it. Inflammation in obesity is the main mechanism leading to comorbid changes. Aim of the study. To establish correlations be…
Introduction. It is assumed that in degenerative diseases of the retina, photostimulation with fractal dynamics signals activates neuroplasticity, increasing the effectiveness of visual rehabilitation. Previously, we demonstrated the positive effect of fractal…
The purpose of the study. To analyze scientific data on the molecular targets and mechanisms of action of key natural bioactive substances used to support cancer patients after chemotherapy and radiation therapy in the framework of personalized medicine. Perso…
Introduction. An increasing number of reports of long-term negative consequences of COVID-19, characterized by chronic inflammation, tissue hypoxia, oxidative stress, metabolic changes at the level of all body systems, determines the search for criteria for as…
Introduction. Recently, a new approach to visual response has been discussed, based on the use of optical signals of a heavy structure, manifested by fractal dynamics. However, the molecular mechanisms of action of fractal phototherapy (FF) have not been studi…
The purpose of the study was to analyze literature data on the use of mesenchymal stem cells as a conservative treatment of osteoarthritis. Material and methods. Literature search was carried out using keywords: traumatology, orthopedics, mesenchymal stem cell…
The purpose of this review was to describe information about the etiology and pathogenesis of the main manifestations in patients with coronavirus infection COVID-19 and the molecular mechanisms of the possible use of metabolite drugs. Material and methods. Th…
A wide range of diseases: stroke, Alzheimer’s disease, brain injury, etc., is based on cerebral hypoperfusion. Vascular dementia, which is the equivalent of cerebral hypoperfusion, is one of the most common cognitive disorders in older people following Alzheim…
Introduction. The androgen receptor (AR) gene MIGHR is known to be associated with transsexualism. Bone tissue is one of the target organs for androgens. Trochanteric index (TI) (ratio of height to the leg length) may indicate the organism androgenization leve…
Introduction. In recent years among non-drug methods of treatment and rehabilitation of patients of elderly and senile age is a promising application of low-intensity millimeter waves as an important reserve of increasing the effectiveness of the complex thera…
Introduction.Study of the influence of molecular and genetic predisposition to forecast neurorehabilitation patients with stroke is of great scientific and practical importance. The aim of the study.Determining the impact of allelic polymorphism Val66Met BDNF …
We have studied BDNF gene Val66Met polymorphism in patients with a high risk of mortality due to stroke or severe head injury. Genotype ValVal rate was higher than that of in the control group in the total sample of subjects (75,5% and 63,6%; χ2=4,63; df=1; p=…