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Molecular Medicine Peer-reviewed scientific journal

Found: 8

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 27–35

USE OF MESENCHYMAL STEM CELLS IN COMPLEX TREATMENT OF DRUG-RESISTANT RENAL TUBERCULOSIS (EXPERIMENTAL STUDY WITH MORPHOLOGICAL CONTROL)

Introduction. The use of mesenchymal stem cells (MSCs) is recognized as a promising direction for the treatment of diseases with a predominance of inflammation and sclerosis in the pathogenesis, which includes nephrotuberculosis (NT). Target. Studying the effe…

10.29296/24999490-2023-05-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

NOVACUTAN PREPARATIONS AS POTENTIAL DERMATOGEROPROTECTORS: MOLECULAR-MICROSCOPIC STUDY

Introduction. The work is devoted to study of new medication Novacutan SBio and Novacutan YBio as potential geroprotectors for biorevitalization of the skin. Klotho was used as a marker – to assess the overall aging of cells; MTH1 – the antioxidant status of c…

10.29296/24999490-2021-04-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

COMPARATIVE EVALUATION OF THE EFFICIENCY OF THE IMPACT OF AQUASHINE LINE PREPARATIONS ON SKIN FIBROBLASTS UNDER AGING IN VITRO (CELL-MOLECULAR RESEARCH)

Introduction. Skin aging is a natural process that cannot be stopped. However, there are many ways to help stop premature aging of the skin and reduce the signs that have already appeared. One of them is the subcutaneous administration of preparations containi…

10.29296/24999490-2019-03-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

THE SOME PECULIARITIES OF CAPSULAR FORMATION AFTER IMPLANTATION OF SILICONE WITH ADSORBED MULTIPOTENT MESENCHYMAL STROMAL CELLS

Introduction. The widespread cellular technologies will sooner or later lead inevitably to the introduction of multipotent mesenchymal stromal cells (MMSC) or their exosomes to patients who have implanted artificial materials in their organism. The engraftment…

10.29296/24999490-2019-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

CARDIOPROTECTIVE EFFECT OF TRIMETAZIDINE IN RATS WITH ESTABLISHED ALCOHOLIC CARDIOMYOPATHY IN THE ABSTINENCE PERIOD

Aim of the study. To study trimetazidine cardioprotective effects on the translation model of alcoholic cardiomyopathy Materials and methods. Alcoholic cardiomyopathy was reproduced in white mongrel male rats used as the sole source of liquid 10% ethanol solut…

10.29296/24999490-2018-01-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

THE INFLUENCE OF FUNCTIONAL POLYMORPHISM IN THE GALANIN PROMOTOR ON GLATIRAMER ACETATE EFFICACY IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

Introduction. Glatiramer acetate (GA, copaxone) – is an immunomodulatory drug, used for reducing the progression of multiple sclerosis. The absence of optimal therapeutic effect in some cases determines the necessity to search the prognostic markers of GA effi…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

THE SPONTANEOUS DELIVERY AFTER CORRECTION OF HYDROMETRA BY ADMINISTRATION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS IN EXPERIMENT

Introduction. The angiogenesis in a uterus scar after application of multipotent mesenchymal stromal cells of a bone marrow origin (MMSCBM) was shown. However, possibility of approach of pregnancy and spontaneous deliveries in rats after MMSCBM introduction in…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

MOLECULAR MECHANISMS OF DERMAL GEROPROTECTIVE ACTION OF DRUGS BASED BIOMIMETIC PEPTIDE

Introduction. Biomimetic peptides – are synthetic compounds which are identical to amino acid sequence that are synthesized by organizm, which can interact with growth factor receptors and provide antiaging clinical effect. The aim of the study. Investigation …

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