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Molecular Medicine Peer-reviewed scientific journal

Found: 3

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 27–32

Comparison of the sensitivity of restriction analysis and PCR with high-resolution melting curve analysis for the detection of the R882H mutation in the DNMT3A gene

Introduction. DNMT3A is one of the most frequently mutated genes in acute myeloid leukemia (AML), and the R882H (G>A) substitution is one of the most common mutations in this gene. Restriction analysis and high resolution melting (HRM) analysis are the most co…

10.29296/24999490-2023-06-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE ANALYSIS OF RASSF1A AND SEMA3B TUMOR SUPRESSOR GENES CPG-ISLANDS METHYLATION STATUS IN UVEAL MELANOMA PATIENTS

Introduction. Uveal melanoma (UM) is a tumor of neuroectodermal origin developing from melanocytes of the uveal tract. The very common pathological characteristic of UM is its metastatic activity in liver, leading to the poor efficiency of the treatment. That`…

10.29296/24999490-2018-01-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

ANALYSIS OF ASSOCIATION BETWEEN THE CHEMOKINE AND CHEMOKINE RECEPTOR GENES AND ESSENTIAL HYPERTENSION

Introduction. Chemokines are a group of proteins that plays an active role in the regulation of the vascular wall inflammation during the development of essential hypertension. The aim of the study was to investigate an association between essential hypertensi…

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