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FREQUENCY OF THE TERT RS2853669 POLYMORPHISM IN MELANOMA PATIENTS RESIDING IN THE EASTERN SIBERIA REGION

Belonogov R.N., Lavrentev S.N., Palkina N.V., Komina A.V., Motorina A.V., Mikhailova A.K., Narkevich A.N., Ruksha T.G.

Introduction. The telomerase reverse transcriptase gene (TERT) promoter region is frequently mutated in different types of cancer. Several studies have shown patients who carry the mutation –245T>C (rs2853669) to have a worse prognosis. The aim of the study is…