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Molecular Medicine Peer-reviewed scientific journal

Found: 2

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 25–32

COMPARATIVE STUDY OF THE SOLUBLE FORMS OF IMMUNE CHECKPOINT PROTEINS VISTA, PD-1, PD-L1, AND BONE HOMEOSTASIS REGULATOR RANKL IN BONE TUMOR PATIENTS

Background. Low sensitivity of bone tumors to various schemes of standard chemotherapy stimulated the search of new targets for their medicamentous treatment. Among such targets are the so-called “immune checkpoints” promoting the escape of the tumor from the …

10.29296/24999490-2022-06-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

RANK/RANKL/OPG SYSTEM COMPONENTS AND INTERLEUKINS 6, 8 16 IN BLOOD SERUM OF PATIENTS WITH PRIMARY BONE NEOPLASMS

Introduction. RANK/RANKL/OPG ligand-receptor system is a key player in bone tissue homeostasis directly regulating osteoclast differentiation and osteolysis. Many pathologic processes imposed by impairments in bone remodeling including tumor growth and metasta…

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