Search

COMPARATIVE STUDY OF THE SOLUBLE FORMS OF IMMUNE CHECKPOINT PROTEINS VISTA, PD-1, PD-L1, AND BONE HOMEOSTASIS REGULATOR RANKL IN BONE TUMOR PATIENTS

Gershtein E.S., Kuzmin Yu.B., Alferov A.A., Korotkova E.A., Tsarapaev P.V., Sokolov N.Yu., Kuznetsov I.N., Vashketova O.I., Kozlova E.M., Yanushevich O.O., Boulytcheva I.V., Stilidi I.S., Kushlinskii N.E.

Background. Low sensitivity of bone tumors to various schemes of standard chemotherapy stimulated the search of new targets for their medicamentous treatment. Among such targets are the so-called “immune checkpoints” promoting the escape of the tumor from the …