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Molecular Medicine Peer-reviewed scientific journal

Found: 4

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

NEW TRANSLATIONAL MODEL OF COGNITIVE DEFICIT IN SCHIZOPHRENIA

Introduction. Taken into account the literature data on the leading role of perceptual deficit in the pathogenesis of schizophrenia and the lack of experimental models of this impairment we proposed the novel test of instinctive aversion (TIA). The work was pe…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

EFFECTS OF CHLORPROMAZINE ON THE N-METHYL-D-ASPARTATE DEPENDENT MECHANISMS OF LONG-TERM POST-TETANIC POTENTIATION FOR UNDERSTANDING OF MENTAL DISORDERS

Introduction. Clinical observations have revealed that the treatment of schizophrenia with the use of chlorpromazine (CPZ) impairs cognitive processes. Whether it is possible to eliminate these side effects of CPZ? The aim of the study. The aim of our study wa…

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ОБЗОР2015

THE PHARMACOGENETIC MECHANISMS OF DEVELOPMENT OF METABOLIC DISORDERS ASSOCIATED WITH THE SECOND-GENERATION ANTIPSYCHOTICS

Antipsychotics are the main medication for schizophrenia treatment. Recently the wideused group of them became second-generation antipsychotics (SGA). Due to that, problem of metabolic disturbances as side effect of SGA is more actually. The development of pha…

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