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Molecular Medicine
Found: 5
Introduction. Bronchial asthma is an inflammatory disease manifested by various phenotypes. The most studied phenotype of asthma is allergic. Molecular allergodiagnostics of allergic diseases using microchips makes it possible to determine the molecular profil…
Introduction. Bronchial asthma is a heterogeneous disease involving different phenotypes. The allergic phenotype is the most studied model of asthma. Identification of causally significant allergens by determining allergen-specific IgE is the key to precision …
The study aims to analyze the dependence of an α1А-adrenoreceptor antagonist effectiveness on G-protein-coupled receptors (GPCRs) intracellular signaling in the passage of medium-sized calculi from the ureter. Material and methods. The study was prospective an…
Аim of the study was to evaluate the activity of receptors that control contraction (α2-adrenergic receptor, purine P2X1 and P2Y receptors, angiotensin AT1 receptor, TxA2 receptor) and relaxation of smooth myocytes (adenosine A2 receptor) during standard litho…
Salinomycin is referred to the group of the polyether antibiotics with ionophore activity. Currently salinomycin is considered as a potential anticancer drug. The aim of this work was to investigate the cytotoxic activity of salinomycin against MDR1+ (Mel-8) a…