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Molecular Medicine Peer-reviewed scientific journal

Found: 3

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

Analysis of biochemical changes in muscular tissue of rats with hypercholesterolemia combined introduction of simvastatin and coenzym Q10

Introduction. Statins are a group of effective lipid – lowering medications. A common side effect of long-term statin use is myopathy. The mechanism of its development is not fully understood at the molecular level, making it difficult to find effective drugs …

10.29296/24999490-2021-05-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

INFLUENCE OF SLCO1B1 GENE C.T521>C POLYMORPHISM ON THERAPY WITH SIMVASTATIN IN CORONARY HEART DISEASE PATIENTS

Introduction. Carrier protein OATP1B1, encoded by the SLCO1B1gene, is involved in the transport of simvastatin into liver cells. SLCO1B1 gene polymorphisms influence on the functionality of the transporter, which could reflect on the efficacy and safety of tre…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

EXPRESSION OF INNATE IMMUNE RECEPTORS AND TRANSCRIPTIONAL REGULATION OF T-HELPER CELLS IN EXPERIMENTAL ILEITIS AND CONDUCT OF THE SIMVASTATIN AND ARIL-1

Introduction. The pathogenesis of inflammatory bowel disease is complex and multifactorial. Studies have led to the current concept that the T-helper cells are components of the adaptive immune response whereas Toll-like receptors, NOD-like-receptors, RIG-I-li…

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