ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021
Mikashinovich Z.I., Semenets I.A.
Introduction. Statins are a group of effective lipid – lowering medications. A common side effect of long-term statin use is myopathy. The mechanism of its development is not fully understood at the molecular level, making it difficult to find effective drugs …
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017
Kotlovskiy M.Yu., Pokrovskiy A.A., Osedko A.V., Osedko O.Ya., Kotlovskaya O.S., Yakimenko A.V., Kurdoyak E.V., Yakimovich I.Yu., Aksyutina N.V., Titova N.M., Kotlovskiy Yu.V., Dygai A.M.
Introduction. Carrier protein OATP1B1, encoded by the SLCO1B1gene, is involved in the transport of simvastatin into liver cells. SLCO1B1 gene polymorphisms influence on the functionality of the transporter, which could reflect on the efficacy and safety of tre…
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016
Zherebiatiev A.S., Kamyshny A.M., Kamyshnaya V.A.
Introduction. The pathogenesis of inflammatory bowel disease is complex and multifactorial. Studies have led to the current concept that the T-helper cells are components of the adaptive immune response whereas Toll-like receptors, NOD-like-receptors, RIG-I-li…