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Molecular Medicine Peer-reviewed scientific journal

Found: 5

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2024 · pp. 38–44

DACARBAZINE INITIATES SIRT1-INDEPENDENT OVEREXPRESSION OF ANTI-APOPTOTIC BCL2 IN MELANOMA CELLS IN VIVO

Introduction. Cancer cell drug resistance in melanoma is associated with evasion of apoptosis-induced stimuli. Assessing the level of expression of the BCL2 and SIRT1 genes in distant organs and the tumor node makes it possible to assess the resistance of mela…

10.29296/24999490-2024-04-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 33–38

Activation of the MAPK signal cascade components phosphorylation involved in the formation of the G0-positive tumor phenotype

Introduction. Among the heterogeneous population of tumor cells, there are so-called dormant and senescent cells located in the G0 phase of the cell cycle. The transition to the G0 phase is a stress response mediated, for example, by treatment with chemotherap…

10.29296/24999490-2023-02-05Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

COMPARATIVE ASSESSMENT OF GROWTH FACTORS EXPRESSION IN PIGMENT NEOPLASMS OF SKIN

Introduction. The study of growth factors in tissues of various kinds of nevi alongside with the skin melanoma can provide valuable information about the pathogenesis of the latter, determine the factors of early diagnostics of melanoma, as well as outline the…

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Research article2014

HORMONAL PATTERN OF MELANOMA AND ITS SURROUNDING TISSUES

Introduction. Skin melanoma is referred to hormone-dependent tumors, the mechanism of influence of endocrine factors on pathogenesis of the tumor, however, has not been determined so far The aim of the study. The studying of the level of steroid hormones, prol…

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