ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021
Mikashinovich Z.I., Semenets I.A.
Introduction. Statins are a group of effective lipid – lowering medications. A common side effect of long-term statin use is myopathy. The mechanism of its development is not fully understood at the molecular level, making it difficult to find effective drugs …
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016
Chertovskikh Ya.V., Shuev G.N., Popova N.V., Rudykh Z.A., Maksimova N. R., Grachev A.V., Sychev D. A.
Introduction. SLCO1B1 encodes the organic anion-transporting polypeptide which has been shown to regulate the hepatic uptake of statins. SLCO1B1*5 genetic variant is associated with the high risk for statin-induced myopathy in patients with statins therapy. Ai…
Research article2014
Shuev G.N., Sychev D.A., Khokhlov A.A., Grachev A.V., Beloshitskaya T.A.
Introduction.SLCO1B1 encodes the organic anion–transporting polypeptide which has been shown to regulate the hepatic uptake of statins. SLCO1B1*5 genetic variant is associated with statin-induced myopathy. The aim of the study. Aim of the study is to research …