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Molecular Medicine Peer-reviewed scientific journal

Found: 6

ОБЗОР2025 · pp. 30–38

Molecular mechanisms of action of natural bioactive compounds in personalized medicine for the rehabilitation of cancer patients after chemo and radiation therapy

The purpose of the study. To analyze scientific data on the molecular targets and mechanisms of action of key natural bioactive substances used to support cancer patients after chemotherapy and radiation therapy in the framework of personalized medicine. Perso…

10.29296/24999490-2025-03-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 71–77

Study of the mutational landscape of primary foci and metastases of papillary carcinoma in the BRAF, KRAS and EGFR genes, their relationship with the clinical characteristics of the tumor

Introduction. Due to the rapidly growing incidence of tumor pathology of the thyroid gland, the range of molecular genetic research methods used to study the targets of targeted drugs, prognosis and surgical tactics is growing. Aim. To study the frequency of m…

10.29296/24999490-2025-02-09Details ↗
ОБЗОР2024 · pp. 40–51

Use of nanotechnology in the creation of targeted drugs for the treatment of oncological diseases

Objective. To analyze current advances in nanotechnology applications for the development of targeted drugs in oncology, including their mechanisms of action and clinical application prospects. Material and methods. A comprehensive analysis of scientific liter…

10.29296/24999490-2024-06-05Details ↗
ОБЗОР2019

THE ROLE OF NF-κB AND von HIPPEL-LINDAU PROTEIN IN THE CREATION OF A MOLECULAR PORTRAIT OF KIDNEY CANCERS

The review presents data on the role of the nuclear factor NF-κB and the von Hippel-Lindau protein (VHL) in the development of kidney cancer. Chemo- and radioresistance, specific for renal cell carcinoma, represented a significant problem in the treatment of p…

10.29296/24999490-2019-03-03Details ↗
Research article2014

SEVERAL GENETIC FEATURES OF HUMAN METASTATIC CUTANEOUS MELANOMA

Introduction. The prevalence of human cutaneous melanoma (CM) in the world is constantly rising. Diagnostics and treatment of CM at the early stages allows to increase the 5-year patient survival up to 90%. This problem can be solved with personalized therapy …

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