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Molecular Medicine Peer-reviewed scientific journal

Found: 12

ОБЗОР2026 · pp. 73–78

Molecular genetic aspects of the pathogenesis of pain syndrome in multiple myeloma

Introduction. This review is devoted to the problem of the pathogenesis of pain syndrome in multiple myeloma (MM). The severity of pain often correlates poorly with the plasma cell burden but is highly dependent on tumor aggressiveness determined by primary ge…

10.29296/24999490-2026-03-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 16–23

ASSESSMENT OF C-REACTIVE PROTEIN, PRESEPSIN AND LIPOPOLYSACCHARIDE-BINDING PROTEIN LEVELS IN CARDIAC SURGERY PATIENTS WITH POSTOPERATIVE INFECTIOUS-INFLAMMATORY COMPLICATIONS

Introduction Postoperative infectious and inflammatory complications worsen the prognosis of patients, increase the duration of hospitalization and increase the cost of treatment, therefore, the search for markers to determine the degree of risk of their devel…

10.29296/24999490-2025-04-03Details ↗
ОБЗОР2024 · pp. 3–12

Immune microenvironment in hepatocellular carcinoma: current concepts and the role of blockade of immune checkpoints

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver. The specificity of the immune microenvironment of an organ limits the possibilities of traditional therapeutic and surgical approaches to treatment, therefore one of the mo…

10.29296/24999490-2024-01-01Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2023 · pp. 53–59

THE GENDER FACTOR EFFECT FOR THE EDOCRYNE FUNCTION OF MESENCHYMAL TISSUES IN CHILDREN AND ADOLESCENT

Introduction. There is take place increasing in the incidence of obesity among children and adolescents in the world. However, until now there are not exist clear views about mechanisms of that phenomenon. The aim of study. The purpose of that work is comparat…

10.29296/24999490-2023-02-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2022 · pp. 20–29

PROGASTRIN-RELEASING PEPTIDE (proGRP) AND NEURON SPECIFIC ENOLASE (NSE) IN SURVIVAL PROGNOSIS IN PATIENTS WITH SMALL CELL LUNG CANCER

Introduction. Small cell lung cancer (SCLS) is a highly aggressive type of tumor, and various compounds are considered as potential biochemical markers of its prognosis, including neuron-specific enolase (NSE), chromogranin A (CgA), and prograstrin releasing p…

10.29296/24999490-2022-03-03Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2020

LIVER ALVEOCOCCOSIS: ULTRASOUND AND MORPHOLOGICAL COMPARISONS

Introduction. Alveococcosis is a parasitic disease associated with the formation of the liver tumor-like lesion. This parasitic tumor has infiltrative growth and the ability to metastasize, that is, it exhibits the properties of malignant tumors. The disease i…

10.29296/24999490-2020-01-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2019

CORRELATION BETWEEN CARDIAC TROPONIN I LEVELS AND AREA OF MYOCARDIAL VASCULAR NECROSIS IN THE PATIENTS WITH FATAL OUTCOME

Introduction. The scale of myocardial infarction plays a key role in the prognosis of the disease. Changes in contractile activity of myocardial tissue as a result of necrosis of cardiomyocytes is the decisive factor in this issue. The aim of the study. The pu…

10.29296/24999490-2019-05-04Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

GENE EXPRESSION OF INTEGRIN RECEPTORS AND THEIR LIGANDS IN PAPILLARY THYROID CARCINOMA WITH DIFFERENT BRAF V600E MUTATION STATUS

Introduction. Papillary thyroid cancer (PTC) is the most common malignancy of the endocrine system. As the most frequent genetic alteration BRAF V600E mutation in PTC leads to changes in the activity of intracellular signaling pathways. As a result, expression…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

MICRORNAS IN ONCOLOGICAL DISEASES

The most important event in the molecular biology of the last years is the discovery of the regulation of intracellular processes by micro RNAs – a product of complicated processing of precursor RNAs synthesized on nuclear genes, that are playing the key role …

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Research article2014

IL1β GENE POLYMORPHISM IN CHRONIC VIRAL HEPATITIS B AND C IN CHILDREN

Introduction. One of the important tasks of hepatology is the prognosis of viral hepatitides. The prognosis is based on the analysis of genetic determination of the functioning of antiviral immunity, particularly, of the cytokine system. The aim of the study w…

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