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Transcription factors bioinformatic analysis of differential gene expression in b16 melanoma cells under antitumor alkylating agent application

Lapkina E.Z., Zinchenko I.S., Bondar Е.I., Ruksha T.G.

Introduction. Cancer drug resistance is driven among others, by non-genetic mechanisms. These processes may involve transcription factors dysregulation, modifications in gene expression, as well as epigenetic mechanisms such as DNA methylation, histone modific…