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Molecular Medicine
Found: 8
Introduction. Lymphogenous metastasis is a key stage in the progression of gastric cancer. The practice of personalized treatment has historically been based on histological and molecular analysis of the primary tumor, while the molecular-genetic landscape of …
Introduction. The liver serves as a buffer for the accumulation and utilization of excess intake of nutritional fats, the intake of plant compounds can improve metabolic processes in the liver, but the molecular mechanisms of this phenomenon have been little s…
Introduction. An actual decision of the issue of safety and effective drug therapy improvement is the development of transport systems that allow to provide targeted delivery of drugs to target cells, while reducing their toxic effects. The aim of the work was…
Introduction. Multiple primary malignant neoplasms (MPMN) most often develop in individuals with a hereditary predisposition to oncological diseases. There are inherited allelic variants of oncogenes, tumor suppressor genes and their combinations which disrupt…
Introduction. The widespread cellular technologies will sooner or later lead inevitably to the introduction of multipotent mesenchymal stromal cells (MMSC) or their exosomes to patients who have implanted artificial materials in their organism. The engraftment…
Pathophysiology as a science and curriculum discipline stands in front of the biggest challenge in its history. It extended farbeyond the limits of its historical name and embedded aspects of Pathochemistry, Immunopathology, Pathobiophysics and Pathoinformatic…
In recent years, scientists from different countries are actively discussing the concept of translational medicine and consider it as important area of molecular medicine development. Translational medicine promotes the transfer of discoveries made in basic bi…
Translational medicine is one of the critical components to overcome the impediments within the objectives of Predictive Preventive and Personalized Medicine. Identification of molecular mechanisms underlying subclinical stages of T1D pathogenesis is a key to …