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Molecular Medicine Peer-reviewed scientific journal

Found: 8

ОБЗОР2023 · pp. 3–12

Imbalance of immunoregulatory molecular cellular mechanisms as a cause of recurrent miscarriage

Introduction. Recurrent pregnancy loss (RPL) is an early spontaneous termination of pregnancy before 20 weeks, which is defined as two or more miscarriages. Most of the known causes associated with the pathophysiology of RPL include endocrine disorders, antiph…

10.29296/24999490-2023-06-01Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

BONE AND MALIGNANT DISEASES OF UTERINE: PROFILE OF EXPRESSION OF GENES OF STEROID RECEPTORS AND TUMOR SUPPRESSOR PTEN

Introduction. Myoma occupies a leading place in the structure of gynecological diseases, reduces the fertility rate and living standardsin females of reproductive age. In 85% cases myoma is combined with adenomyosis, which complicates the treatment and increas…

10.29296/24999490-2018-03-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2017

GROWTH FACTORS AND PLASMINOGEN ACTIVATION SYSTEM IN TUMORS OF THE ORGANS OF THE FEMALE REPRODUCTIVE SYSTEM

Background. Plasminogen activators play the leading role in the tumor growth and metastasis. Growth factors stimulate proliferative processes and are involved in neoangiogenesis. Aim of the study. Identification of changes in components of the fibrinolysis sys…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

ASSOCIATIONS OF CANDIDATE GENES IN THE FORMATION OF UTERINE FIBROIDS

Introduction. Uterine fibroids – a benign tumor, growing from immature muscle cells of the vascular wall of the uterus. It ranked first among the benign tumors of the genital organs, with one in ten suffers from gynecological patients with uterine myoma. The a…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2016

SEX HORMONES AS REGULATORS OF THE LEVEL OF GROWTH FACTORS IN TUMOR TISSUES IN POLYNEOPLASIA OF FEMALE REPRODUCTIVE ORGANS

Introduction. Sex hormones are known to influence on synthesis of growth factors in breast and uterus tumors, but their correlation in polyneoplasias is poorly studied. The aim of the study. The analyze local steroidogenesis, synthesis of growth factors and th…

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

THE SPONTANEOUS DELIVERY AFTER CORRECTION OF HYDROMETRA BY ADMINISTRATION OF MULTIPOTENT MESENCHYMAL STROMAL CELLS IN EXPERIMENT

Introduction. The angiogenesis in a uterus scar after application of multipotent mesenchymal stromal cells of a bone marrow origin (MMSCBM) was shown. However, possibility of approach of pregnancy and spontaneous deliveries in rats after MMSCBM introduction in…

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