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THE ROLE OF NF-κB AND von HIPPEL-LINDAU PROTEIN IN THE CREATION OF A MOLECULAR PORTRAIT OF KIDNEY CANCERS

Spirina L.V., Slonimskaya E.M., Yurmazov Z.A., Usynin E.A., Lushnikova N.A., Tarasenko N.V., Kondakova I.V.

The review presents data on the role of the nuclear factor NF-κB and the von Hippel-Lindau protein (VHL) in the development of kidney cancer. Chemo- and radioresistance, specific for renal cell carcinoma, represented a significant problem in the treatment of p…