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Molecular Medicine Peer-reviewed scientific journal

Found: 5

ОБЗОР2026 · pp. 100–106

Molecular predictors of efficacy of single-stranded yeast RNA and ascorbic acid complexes: from critical quality attributes to personalized immunomodulation

Introduction. Single-stranded yeast RNA–ascorbic acid complexes are of interest as a class of natural immunomodulatory systems combining activation of innate immune pattern-recognition receptors with redox-modulating and epigenetic effects of vitamin C. Russia…

10.29296/24999490-2026-03-14Details ↗
ОБЗОР2026 · pp. 65–74

YEAST RNA AS A SOURCE OF IMMUNOMODULATORY NUCLEOTIDES: FROM BIOCHEMISTRY TO CLINICAL APPLICATION

Introduction. Yeast RNA is considered a promising class of natural immunomodulators that has been studied in Russian biomedical science since the Soviet period. High-molecular-weight RNA fractions from Saccharomyces cerevisiae exhibit pronounced immunostimulat…

10.29296/24999490-2026-02-09Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2025 · pp. 45–53

Molecular analysis of sensitization by aeroallergens in adult patients with allergic bronchial asthma

Introduction. Bronchial asthma is an inflammatory disease manifested by various phenotypes. The most studied phenotype of asthma is allergic. Molecular allergodiagnostics of allergic diseases using microchips makes it possible to determine the molecular profil…

10.29296/24999490-2025-02-06Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2021

EFFECT OF IMMOBILIZATION OF GLYCOPROTEINS OF THE BAKER’S YEAST CELL WALL ON THEIR IMMUNOMODULATORY ACTIVITY

The aim of the study was to study the effect of chemical immobilization of yeast cell wall glycoproteins on their ability to activate cytokine production by human peripheral blood cells. Methods. A comparative analysis of the immunomodulatory activity of yeast…

10.29296/24999490-2021-06-08Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

SТIMULATION OF SIGNALING RECEPTORS GENE EXPRESSION AND INDUCTION OF SYNTHESIS OF CYTOKINES IN HUMAN BLOOD CELLS BY DRUG RIBONUCLEAT SODIUM AND ITS COMBINATION WITH INACTIVATED INFLUENZA VACCINES

Introduction. Russian drug Ribonucleate sodium (mixture of yeast ssRNA and dsRNA) possesses of the wide spectrum of antiviral and immunomodulation actions, it improves the efficacy of inactivated vaccines in experimental animals. It can activate IFN-system gen…

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