ASSESSMENT OF THE EFFECTIVENESS OF THROMBOLYTIC THERAPYOF PULMONARY TROMBOEMBOLISM BY LUNG PERFUSION SCANNING

Assessment of the effectiveness of thrombolytic and anticoagulation therapies was performed in 92 patients with pulmonary
tromboembolism (PTE), aged from 22 to 88 years (average age is 59,3±13,9 years). In accordance with the diagnostics algorithm of
PTE, accepted in our hospital, complex of methods included: x-ray of lungs (for the exception of chronic diseases or damage of the lungs),
ultrasound examination of veins of lower extremities and v. cava inferior, lung perfusion scanning (LPS), and in some cases – CTPA of the
lungs in continuing doubts about the diagnosis. The detection of the perfusion deficit and assessment of the recovery of the lung perfusion were
performed with radionuclide method. The study showed that if compared with anticoagulant a thrombolytic therapy had a significant effect,
which contributed to the total restoration or improvement of perfusion in the pulmonary circulation in 92,1% of patients sought for medical
advice within the first nine days after onset of the disease.

E.V. Migunova, Kudryashova N.E., Nikitina O.V., Beresneva E.A., Gol'dina I.M., Zabavskaya O.A., Sinyakova O.G., Mikhaylov I.P., Kosolapov D.A., Kungurtsev E.V.
Sklifosovsky Research Institute for Emergency Medicine, Moscow