This website is intended for professionals in medicine and healthcare. By selecting “Confirm”, I declare that I am a member of this professional audience. I also agree to the publisher’s rules for using its information resource. Publisher’s resource rules (Russian)
The development of allergic reactions to beta-lactam antibiotics is largely determined by genetic factors. In this work, to study the
association of gene polymorphisms IL-4Rα (rs1801275) with the development of immediate hypersensitivity reactions (RGNT) to betalactam
antibiotics in the russian population of patients genotypic frequencies of rs1801275 polymorphism of this gene were investigated. The
study showed a statistically significant difference in the gene polymorphism IL-4Rα (rs1801275) between the control group and the group
of patients with RGNT to beta-lactam antibiotics. The association between the development of IRR to beta-lactam antibiotics and genotype
AARGNT in russian patients was demonstrated (OR=3,50; CI95% [1,82–6,72]; р=0,0001).
I.E. Groznova, A.O. Chikalo, N.G. Berdnikova, D.A. Sychev, V.G. Kukes
Scientific Centre of Medical Products, Moscow, Russian Federation
How to cite
Groznova I.E., Chikalo A.O., Berdnikova N.G., Sychev D.A., Kukes V.G. (2013). ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS. Molecular Medicine, (2).
Groznova I.E., Chikalo A.O., Berdnikova N.G., Sychev D.A., Kukes V.G., “ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS”, Molecular Medicine, no. 2, 2013.
Groznova I.E., Chikalo A.O., Berdnikova N.G., Sychev D.A., Kukes V.G. “ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS.” Molecular Medicine, no. 2, 2013,
Groznova I.E., Chikalo A.O., Berdnikova N.G., Sychev D.A., Kukes V.G. 2013. “ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS.” Molecular Medicine (2).
Groznova I.E., Chikalo A.O., Berdnikova N.G., Sychev D.A., Kukes V.G. (2013) ‘ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS’, Molecular Medicine, (2).
Groznova I.E., Chikalo A.O., Berdnikova N.G., Sychev D.A., Kukes V.G. ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS. Molecular Medicine. 2013;(2).
TY - JOUR
TI - ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS
AU - Groznova I.E.
AU - Chikalo A.O.
AU - Berdnikova N.G.
AU - Sychev D.A.
AU - Kukes V.G.
JO - Molecular Medicine
PY - 2013
IS - 2
UR - https://new.molmedjournal.ru/en/molecmed-2013-02-08
ER -
@article{article184,
title = {ASSOCIATION OF IL-4Rα POLYMORPHISM WITH THE DEVELOPMENTOF IMMEDIATE HYPERSENSITIVITY REACTIONS TO BETA-LACTAM ANTIBIOTICS},
author = {Groznova I.E. and Chikalo A.O. and Berdnikova N.G. and Sychev D.A. and Kukes V.G.},
journal = {Molecular Medicine},
year = {2013},
number = {2},
}
