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Molecular Medicine Peer-reviewed scientific journal

Found: 27

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

CONCENTRATION OF INTERLEUKINES IN BLOOD PLASMA IN PATIENTS WITH CHRONIC CEREBRAL ISCHEMIA – CARRIERS OF ANTI-INFLAMMATORY CYTOKINES GENES POLYMORPHISMS

Introduction. There were examined 195 patients with chronic сerebrovasсular pathology and 149 healthy residents of the Zabaykalsky region. The aim of the study. Detection of genetic polymorphism in cytokines IL4-589С>T, IL10-1082G>A, IL10-819C>T, IL10-592C>A, …

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

APPLICATION OF PHARMACOGENETICS TESTING IN PATIENTS WITH CARDIAC VALVE REPLACEMENT

Introduction. Pharmacogenetic testing allows of increasing efficacy of anticoagulation therapy, reducing time required for adjusting therapeutic dose, and considerably reducing number of complications. The aim of the study. To investigate the dependence of the…

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Research article2014

EVOLUTIONARY MEDICAL GENOMICS

«Nothing in biomedicine makes sense except in the light of evolution». From this point of view, genetics of predispositions hasto answer two basic questions: 1. Is the natural genetic polymorphism identified with modern genomics proved to be the result of neut…

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Research article2013

ANALYSIS OF GENETIC POLYMORPHISMS IN ESTROGENMETABOLIZING ENZYMES IN OVARIAN CANCER PATIENTS IN THE SIBERIA REGION

Early diagnosis of ovarian cancer (OC) remains to be the actual problem in modern oncology due to the high mortality rate, asymptomatic course of the disease in the early stages and its aggressiveness. The aim was to study the genetic polymorphism of pathogene…

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Research article2012

INFLUENCE OF D-1208I GENE POLYMORPHISM ON TISSUE FACTOR ACTIVITY

reduced levels of monocytic TF expression in comparison with homozygous ones (160,1±53,0% and 198,6±72,9% M±SD, accordingly). If compared with homozygous allelic variants D-1208I heterozygous genotype is associated with less macrophagic TF expression in lungs …

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ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ

THE ROLE OF SOME GENETIC POLYMORPHISMS OF IL-10 IN THE DEVELOPMENT OF VARICELLA IN MILITARY PERSONNEL

Introduction. Currently, scientists are paying increasing attention to the genetic condition of various pathologies. According to recent studies, cytokines play an essential role in the immune response in various pathological processes. The detection of geneti…

10.29296/24999490-2022-01-10Details ↗

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