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Molecular Medicine Peer-reviewed scientific journal

Found: 27

ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

INVESTIGATIONS OF THE 125I-LABELLED TARGET MOLECULES DARPIN9_29 FOR RADIONUCLIDE DIAGNOSTICS OF MALIGNANT TUMORS WITH HER2/NEU OVEREXPRESSION

Introduction. Her2/neu is one of the most studied molecular target the overexpression of which is associated with poor prognosis and aggressive course of the disease. The use of modern non-invasive radionuclide techniques with the application of highly affinit…

10.29296/24999490-2018-06-07Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2018

THE ROLE OF STEROID ER, AR RECEPTORS, BRN-3Α AND TRIM16 NUCLEAR TRANSCRIPTION FACTORS IN THE DEVELOPMENT OF KIDNEY CANCER

Introduction. The study of molecular mechanisms of the development of kidney cancer is one of the actual problems in oncology. There is conflicting information about the importance of steroid hormone receptors in the kidney cancer. The aim of the study was to …

10.29296/24999490-2018-05-10Details ↗
ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ2015

ASSOCIATION OF CANCER MOLECULAR PARAMETERS WITH EFFECTIVENESS OF PAZOPANIB TREATMENT IN ADVANCED KIDNEY CANCER PATIENTS

Introduction. The search for criteria for the prediction of the efficacy of targeted therapies will allow not only to optimize the readings, but also to improve the results of treatment of patients with metastatic kidney cancer. The aim of the study is the inv…

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Research article2013

MODIFICATION OF PROTEIN MOLECULES UNDER ENDOGENOUS INTOXICATIONAS A RISK FACTOR OF CHRONIC METABOLIC DISEASES

The enhancement of ligand properties of protein molecules treated by toxic reagents has been revealed in model experiments in vitro on ordered protein films. In patients with endogenous intoxication caused by metabolic disorders there were also detected protei…

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Research article2013

BLOOD SERUM REDOX POTENTIAL AND ANTIOXIDANT ACTIVITY COMPARISON

Electrochemical method of antioxidants level determination in biological media was developed. The comparison of the blood serum redox potential and antioxidant activity for practically health people (n=31) was carried out. The effect of added antioxidants and …

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